AKUSHERLIK VA GINEKOLOGIYADA BIRIKTIRUVCHI TOʻQIMA DIFFERENSIALLASHMAGAN DISPLAZIYASI DIAGNOTIKASINING JIHATLARI
DOI:
https://doi.org/10.47390/3030-3133V1I2Y2023N08Kalit so'zlar:
biriktiruvchi toʻqima differensiallashmagan displaziyasi, magniy, oksiprolin, muddatidan oldingi tugʻruq, xavf soluvchi abort, magniy preparatlari, homiladorlik.Annotatsiya
Tadqiqotning maqsadi biriktiruvchi toʻqima differensiallashmagan displaziyasi (BTDD) mavjud homiladorlarda biriktiruvchi toʻqima metabolizmi biokimyoviy markerlari – qondagi magniy va oksiprolin miqdorini aniqlashning samaradorligini aniqlash va buni magniy preparatlari bilan davolash yordamida tekshirishdan iborat. Tadqiqot Toshkent shahar 9-Akusherlik kompleksida oʻtkazilgan. Unga 129 ta ayol qamrab olindi. Ulardan 65 tasi sogʻlom ayollar boʻlib, 64 tasida esa BTDD mavjud. Tadqiqot natijalariga koʻra, BTDD mavjud homiladorlarda nazorat guruhi bilan solishtirganda qondagi oksiprolin miqdori yuqoriroq, magniy miqdori esa kamroqligi aniqlandi. Shuningdek, magniy preparatlari qabul qilish bu koʻrsatkichlar me’yorllashishiga olib kelgan. Tadqiqot xulosasi boʻyicha, BTDD mavjud homiladorlarda qondagi magniy hamda oksiprolin miqdorini aniqlash ularda homiladorlikni olib borishda muhim hisoblanadi.
Foydalanilgan adabiyotlar
Boivin D.B., Boudreau P., Kosmadopoulos A. Disturbance of the Circadian System in Shift Work and Its Health Impact. J. Biol. Rhythm. 2022; 37:3–28. doi: 10.1177/07487304211064218.
Chaput J.P., McHill A.W., Cox R.C., Broussard J.L., Dutil C., da Costa B.G.G., Sampasa-Kanyinga H., Wright K.P., Jr. The role of insufficient sleep and circadian misalignment in obesity. Nat. Rev. Endocrinol. 2023; 19:82–97. doi: 10.1038/s41574-022-00747-7.
Chellappa S.L., Vujovic N., Williams J.S., Scheer F. Impact of Circadian Disruption on Cardiovascular Function and Disease. Trends Endocrinol. Metab. TEM. 2019; 30:767–779. doi: 10.1016/j.tem.2019.07.008.
Dun, A.; Zhao, X.; Jin, X.; Wei, T.; Gao, X.; Wang, Y.; Hou, H. Association between Night-Shift Work and Cancer Risk: Updated Systematic Review and Meta-Analysis. Front. Oncol. 2020, 10, 1006.
Dutheil F., Baker J.S., Mermillod M., De Cesare M., Vidal A., Moustafa F., Pereira B., Navel V. Shift work, and particularly permanent night shifts, promote dyslipidaemia: A systematic review and meta-analysis. Atherosclerosis. 2020; 313:156–169. doi: 10.1016/j.atherosclerosis.2020.08.015.
Fatima N., Rana S. Metabolic implications of circadian disruption. Pflug. Arch. Eur. J. Physiol. 2020; 472:513–526. doi: 10.1007/s00424-020-02381-6.
Fernandez R.C., Moore V.M., Marino J.L., Whitrow M.J., Davies M.J. Night Shift Among Women: Is It Associated with Difficulty Conceiving a First Birth? Front. Public Health. 2020; 8:595943. doi: 10.3389/fpubh.2020.595943.
Fishbein A.B., Knutson K.L., Zee P.C. Circadian disruption and human health. J. Clin. Investig. 2021;131: e148286. doi: 10.1172/JCI148286.
Gentry N.W., Ashbrook L.H., Fu Y.H., Ptáček L.J. Human circadian variations. J. Clin. Investig. 2021;131: e148282. doi: 10.1172/JCI148282.
Hulsegge G., Picavet H.S.J., van der Beek A.J., Verschuren W.M.M., Twisk J.W., Proper K.I. Shift work, chronotype and the risk of cardiometabolic risk factors. Eur. J. Public Health. 2019; 29:128–134. doi: 10.1093/eurpub/cky092.
Iwasaki M., Hirose T., Mita T., Sato F., Ito C., Yamamoto R., Someya Y., Yoshihara T., Tamura Y., Kanazawa A., et al. Morningness-eveningness questionnaire score correlates with glycated hemoglobin in middle-aged male workers with type 2 diabetes mellitus. J. Diabetes Investig. 2013; 4:376–381. doi: 10.1111/jdi.12047.
Khan S., Malik B.H., Gupta D., Rutkofsky I. The Role of Circadian Misalignment due to Insomnia, Lack of Sleep, and Shift Work in Increasing the Risk of Cardiac Diseases: A Systematic Review. Cureus. 2020;12: e6616. doi: 10.7759/cureus.6616.
Khosravipour M., Khanlari P., Khazaie S., Khosravipour H., Khazaie H. A systematic review and meta-analysis of the association between shift work and metabolic syndrome: The roles of sleep, gender, and type of shift work. Sleep Med. Rev. 2021; 57:101427. doi: 10.1016/j.smrv.2021.101427.
Klerman E.B., Brager A., Carskadon M.A., Depner C.M., Foster R., Goel N., Harrington M., Holloway P.M., Knauert M.P., LeBourgeois M.K., et al. Keeping an eye on circadian time in clinical research and medicine. Clin. Transl. Med. 2022;12: e1131. doi: 10.1002/ctm2.1131.
Koopman A.D.M., Rauh S.P., van ’t Riet E., Groeneveld L., van der Heijden A.A., Elders P.J., Dekker J.M., Nijpels G., Beulens J.W., Rutters F. The Association between Social Jetlag, the Metabolic Syndrome, and Type 2 Diabetes Mellitus in the General Population: The New Hoorn Study. J. Biol. Rhythm. 2017; 32:359–368. doi: 10.1177/0748730417713572.
Loloei S., Sepidarkish M., Heydarian A., Tahvilian N., Khazdouz M., Heshmati J., Pouraram H. The effect of melatonin supplementation on lipid profile and anthropometric indices: A systematic review and meta-analysis of clinical trials. Diabetes Metab. Syndr. 2019; 13:1901–1910. doi: 10.1016/j.dsx.2019.04.043.
Man A.W.C., Li H., Xia N. Circadian Rhythm: Potential Therapeutic Target for Atherosclerosis and Thrombosis. Int. J. Mol. Sci. 2021; 22:676. doi: 10.3390/ijms22020676.
Manouchehri E., Taghipour A., Ghavami V., Ebadi A., Homaei F., Latifnejad Roudsari R. Night-shift work duration and breast cancer risk: An updated systematic review and meta-analysis. BMC Women’s Health. 2021; 21:89. doi: 10.1186/s12905-021-01233-4.
