ANALYSIS OF LIPID SPECTRUM PARAMETERS IN PATIENTS WITH COVID-19 AND CHRONIC RENAL DISEASE

Authors

  • Dilrukh Madazimova

DOI:

https://doi.org/10.47390/Med-pro/v3i6y2025/N04

Keywords:

COVID-19, lipid spector, coronavirus infection, HDL, THL, LDL

Abstract

Hyperlipidemia is one of the main metabolic factors in chronic kidney disease. Most people with a high mortality rate from coronavirus infection suffer from obesity, diabetes mellitus and other metabolic disorders. In many studies, patients with COVID-19 infection have seen a decrease in HDL levels, an increase in THL and LDL levels

References

1. Арутюнов Г. П., Тарловская Ye. И., Арутюнов А. Г. и др. Вновь диагностированные заболевания и частота их возникновения у пациентов после новой коронавирусной инфекции. Результаты международного регистра "Анализ динамики коморбидных заболеваний у пациентов, перенесших инфицирование SARS-CoV-2)" (12 месяцев наблюдения). Российский кардиологический журнал. 2023;28(4):5424. https://doi.org/10.15829/1560-4071-2023-5424

2. Płazak W, Drabik L. SARS-CoV-2 infection and SLE: endothelial dysfunction, atherosclerosis, and thrombosis. Clin Rheumatol. 2023:112. https://doi.org/10.1007/ s10067-022-06497-1.

3. Арутюнов Г. П., Тарловская Е. И., Арутюнов А. Г. и др. Анализ показателей липидного спектра у госпитализированных пациентов с COVID-19 в зависимости от исхода острого периода инфекции по данным международного регистра "Анализ динамики Коморбидных заболеваний у пациенТов, перенесшИх инфицироВание SARS-CoV-2". Российский кардиологический журнал. 2022;27(9):5042. https://doi.org/10.15829/1560-4071-2022-5042

4. Fan J, Wang H, Ye G, et al. Letter to the Editor: Low-density lipoprotein is a potential predictor of poor prognosis in patients with coronavirus disease 2019. Metabolism. 2020;107:154243. https://doi.org/10.1016/j.metabol.2020.154243

5. Hu X, Chen D, Wu L, et al. Declined serum high density lipoprotein cholesterol is associated with the severity of COVID-19 infection. Clin Chim Acta. 2020;510:105-10. https://doi.org/10.1016/j.cca.2020.07.015

6. Wei X, Zeng W, Su J, et al. Hypolipidemia is associated with the severity of COVID-19. J Clin Lipidol. 2020;14(3):297-304. https://doi.org/10.1016/j.jacl.2020.04.008

7. Fernández-Friera L, Fuster V, López-Melgar B, et al. Normal LDL-Cholesterol Levels Are Associated With Subclinical Atherosclerosis in the Absence of Risk Factors. J Am Coll Cardiol. 2017;70(24):297991. https://doi.org/10.1016/j.jacc.2017.10.024

8. Lee H, Ahn HJ, Park HE, et al. The effect of non-optimal lipids on the progression of coronary artery calcification in statin-naïve young adults: results from KOICA registry. Front Cardiovasc Med. 2023;10:1173289. https://doi.org/10.3389/fcvm.2023.1173289

9. Brunner FJ, Waldeyer C, Ojeda F, et al. Multinational Cardiovascular Risk Consortium. Application of non-HDL cholesterol for population-based cardiovascular risk stratification: results from the Multinational Cardiovascular Risk Consortium. Lancet. 2019;394(10215):2173-83. https://doi.org/10.1016/S0140-6736(19)32519-X

10. He X, Liu C, Peng J, et al. COVID-19 induces new-onset insulin resistance and lipid metabolic dysregulation via regulation of secreted metabolic factors. Signal Transduct. Target. Ther. 2021;6:427. https://doi.org/10.1038/s41392-021-00822-x.

11. Bizkarguenaga M, Bruzzone C, Gil-Redondo R, et al. Uneven metabolic and lipidomic profiles in recovered COVID-19 patients as investigated by plasma NMR metabolomics. NMR Biomed. 2022;35:e4637. https://doi.org/10.1002/nbm.4637 .

12. Washirasaksiri C, Sayabovorn N, Ariyakunaphan P, et al. Long-term multiple metabolic abnormalities among healthy and high-risk people following nonsevere COVID-19. Sci Rep. 2023;13(1):14336. https://doi.org/10.1038/s41598-023-41523-5

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Published

2025-10-11

How to Cite

Madazimova , D. (2025). ANALYSIS OF LIPID SPECTRUM PARAMETERS IN PATIENTS WITH COVID-19 AND CHRONIC RENAL DISEASE. MedicineProblems.Uz-Topical Issues of Medical Sciences, 3(6), 20–23. https://doi.org/10.47390/Med-pro/v3i6y2025/N04