ANALYSIS OF CHANGES IN LIVER ENZYMES UNDER THE INFLUENCE OF ANTIVIRAL DRUGS IN PATIENTS WITH COVID-19

Authors

  • Guzel Sabirova
  • Zarnigor Bafoeva

Keywords:

Covid-19, favipiravir, remsidivir, ALT, AST.

Abstract

This article told about 110 patients who were treated in June 2021 at the Republican Special Hospital No. 2 of Zangiot, where the diagnosis of coronavirus was confirmed. In general, Covid- 19 of mild and moderate severity was detected in patients. The patients underwent a standard course of treatment on the recommendation of WHO. The standard treatment plan includes medications like favipiravir and remsidivir. A biochemical blood test was performed every three days, and changes in the analysis were dynamically monitored. It was found that patients mainly had liver disorders, especially ALT and AST were 2 and 3 times higher than normal. At the end of the course of treatment with antiviral drugs, a slow decrease in the level of enzymes was observed.

References

Desai MK. Pharmacovigilance and assessment of drug safety reports during COVID 19. Perspect Clin Res. 2020;11(3):128. DOI:10.4103/picr.PICR_171_20

Singh TU, Parida S, Lingaraju MC, et al. Drug repurposing approach to fight COVID-19. Pharmacol Rep. 2020;72:1479-508. DOI:10.1007/s43440-020-00155-6

World Health Organization. Rolling updates on coronavirus disease (COVID-19)(Updated18April2020). https://www.who.int/emergencies/diseases/novel-coro-navirus-2019/events-as-they-happen. Accessed Apr 21, 2020.

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Published

2023-10-24

How to Cite

Sabirova , G., & Bafoeva , Z. (2023). ANALYSIS OF CHANGES IN LIVER ENZYMES UNDER THE INFLUENCE OF ANTIVIRAL DRUGS IN PATIENTS WITH COVID-19. MedicineProblems.Uz-Topical Issues of Medical Sciences, 1(1), 50–56. Retrieved from https://medicineproblems.uz/index.php/journal/article/view/14