THE ROLE OF MODERN BIOMARKERS IN THE EVALUATION OF PROFIBROTIC PROCESSES IN SYSTEMIC SCLEROSIS
DOI:
https://doi.org/10.47390/Med-pro/v3i7y2025/N07Keywords:
systemic sclerosis, fibrosis, biomarkers, TGF-β1, endothelin-1, MMP-9, TIMP-1, CTGF.Keywords: systemic sclerosis, fibrosis, biomarkers, TGF-β1, endothelin-1, MMP-9, TIMP-1, CTGF, pulmonary fibrosis, fibrogenesis.Abstract
The diagnostic and prognostic significance of fibrogenesis biomarkers (TGF-β1, endothelin-1, MMP-9, TIMP-1, CTGF) was evaluated in 37 systemic sclerosis patients. Elevated TGF-β1, TIMP-1, and CTGF correlated with fibrosis severity, reflecting disease activity.
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